C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01) A61K 31/4196 (2006.01) A61P 3/10 (2006.01)
Patent
CA 2572136
The invention relates to imidazoles and triazoles of general formula (I) wherein R1 to R4 and X have the designations cited in patent claims 1 to 8. The invention also relates to the tautomers, enantiomers, diastereomers, mixtures and salts thereof, which have valuable pharmacological properties, especially an inhibiting action on the activity of the enzyme dipeptidylpeptidase-IV (DPP-IV).
La présente invention concerne des imidazoles et des triazoles de formule générale (I) dans laquelle R1 à R4 et X sont tels que définis dans les revendications 1 à 8, ainsi que des tautomères, énantiomères, diastéréo-isomères, mélanges et sels de ceux-ci, qui présentent des propriétés intéressantes d'un point de vue pharmacologique, en particulier un effet inhibiteur sur l'activité de l'enzyme dipeptidyl peptidase IV (DPP-IV).
Eckhardt Matthias
Himmelsbach Frank
Langkopf Elke
Tadayyon Mohammad
Thomas Leo
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
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