Preventives and remedies for diffuse lung disease

A - Human Necessities – 61 – K

Patent

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IPC codes

A61K 39/395 (2006.01) A61K 45/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12P 21/08 (2006.01) A61K 38/00 (2006.01)

Type

Patent

Patent number

CA 2309598

Description

Preventives and remedies for diffuse lung diseases whereby apoptosis can be inhibited and thus favorable preventive/therapeutic effects can be established. These drugs contain apoptosis-inhibiting substances as the active ingredient. The above apoptosis-inhibiting substances include Fas antagonists and Fas-Fas ligand bond inhibitors such as Fas derivatives and anti-Fas ligand antibodies.

La présente invention concerne des médicaments préventifs et thérapeutiques dirigés contre des affections pulmonaires diffuses. Ils opèrent par blocage de l'apoptose ce qui permet d'induire des effets préventifs et thérapeutiques. Les principes actifs de ces médicaments sont des substances inhibitrices de l'apoptose. Ces substances inhibitrices de l'apoptose sont principalement des antagonistes Fas et des inhibiteurs de liaison aux ligands Fas-Fas tels que des dérivés Fas et des anticorps à ligands anti-Fas.

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