Uses of hmgb, hmgn, hmga proteins

G - Physics – 01 – N

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G01N 33/574 (2006.01) A61K 6/00 (2006.01) A61K 8/60 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) A61Q 19/00 (2006.01) C07K 14/47 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2512512

The invention relates to the use, especially in vitro, of one or more nucleic acids, the transcription product(s) thereof and/or the translation product(s) thereof for a process. Said process is selected from the group including angiogenesis, neovascularization, transmyocardial revascularization, wound healing, wound bed angiogenesis, epithelization and healing in of dental and bone implants. The nucleic acid(s) is/are selected from the group including the genes for high mobility group proteins.

L'invention concerne l'utilisation, en particulier in vitro, d'un ou de plusieurs acide(s) nucléique(s), du/des produit(s) de transcription correspondant(s) et/ou du/des produit(s) de traduction correspondant(s) pour un processus, ce processus étant sélectionné dans un groupe comprenant les processus suivants : angiogenèse, néovascularisation, revascularisation transmyocardique, guérison de plaies, angiogenèse dans le lit d'une plaie, épithélialisation, et intégration et guérison après la mise en place d'implants dentaires et osseux. Selon l'invention, le(s)dit(s) acide(s) nucléique(s) est/sont sélectionné(s) dans le groupe comprenant des gènes de protéines du groupe de haute mobilité (HMG).

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