A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/14 (2006.01) A61K 31/216 (2006.01) A61K 31/4025 (2006.01) A61K 31/445 (2006.01) A61K 31/47 (2006.01)
Patent
CA 2522666
The invention features a method of treating asthma, COPD, allergic rhinitis, and infectious rhinitis by administering a first pharmaceutical agent including one or more compounds selected from the quarternary ammonium compounds of formulae I~ V and a second pharmaceutical agent including one or more pharmaceutical agents selected from Adenosine A2a Receptor Agonists, D2- Dopamine Receptor Agonists, Phosphodiesterase Inhibitors (PDE's), corticosteroids, norepinephrine reuptake inhibitors, 4-hydroxy-7-[2-[2-[3- [2- phenylethoxy]- propylsulphonyllethylamino] ethyl] -1,3-benzothiazol-2(3H)-one, and pharmaceutically acceptable salts thereof, and non-quarternized antimuscarinic compounds.
L'invention concerne une méthode pour traiter l'asthme, la DPCO, la rhinite allergique et la rhinite infectieuse en administrant au patient un premier agent pharmaceutique renfermant un ou plusieurs composés choisis parmi les composés d'ammonium quaternaire des formules (I-V), et un deuxième agent pharmaceutique renfermant un ou plusieurs agents pharmaceutiques choisis parmi des agonistes du récepteur A¿2a? de l'adénosine, des agonistes du récepteur dopaminergique D2, des inhibiteurs de la phosphodiestérase, des corticostéroïdes, des inhibiteurs de recaptage de la noradrénaline, de la 4-hydroxy-7-[2-[2-[3-[2-phényléthoxy]-propylsulfonyléthylamino] éthyl]-1,3-benzothiazol-2(3H)-one, et leurs sels pharmaceutiquement acceptables, ainsi que des composés antimuscariniques non quaternisés.
Manning Robert Everett
Richards Ivan Michael
Pharmacia & Upjohn Company Llc
Smart & Biggar
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