C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 311/04 (2006.01) A61K 31/352 (2006.01) A61K 45/06 (2006.01) C07D 311/16 (2006.01) C07D 311/18 (2006.01) C07D 311/58 (2006.01)
Patent
CA 2493913
A class of chromane and chromene compounds having the structure shown below and pharmaceutically acceptable salts thereof are useful as therapeutic compounds, particularly in the treatment and control of hyperlipidemia, hypercholesterolemia, dyslipidemia, and other lipid disorders, and in delaying the onset of or reducing the risk of conditions and sequelae that are associated with these diseases, such as atherosclerosis.
L'invention concerne une classe de chromane et des composés de chromène de structure indiquée ci-dessous, et leurs sels pharmaceutiquement acceptables, qui sont utiles comme composés thérapeutiques, en particulier dans le traitement et le contrôle de l'hyperlipidémie, l'hypercholestérolemie, la dyslipidémie et autres troubles lipidiques. Ils sont également utiles en ce qu'ils retardent l'apparition de ou diminuent le risque d'affections et de séquelles associées à ces maladies, telles que l'athérosclérose.
Desai Ranjit C.
Sahoo Soumya
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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