Heparin fragments as inhibitors of smooth cell proliferation

A - Human Necessities – 61 – K

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167/139, 167/199

A61K 39/395 (2006.01) A61K 31/70 (2006.01) C07H 3/06 (2006.01) C07H 11/00 (2006.01) C07H 13/04 (2006.01)

Patent

CA 2005739

-26- Abstract A glycosaminoglycoside (GAG) composition predominantly of tetrasaccharide units derived from heparin/heparan sulfate has enhanced activity in preventing the proliferation of smooth muscle cells. This GAG preparation is useful in the treatment of diseases characterized by unwanted smooth muscle cell proliferation and activity.

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