C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61P 17/06 (2006.01) A61P 35/00 (2006.01) C07K 16/22 (2006.01) C12N 5/18 (2006.01) C12P 21/08 (2006.01) C12Q 1/00 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2515081
The present invention is directed to anti-AR antibodies, preferably humanized monoclonal antibodies having the amino acid sequences disclosed herein. The present invention includes a pharmaceutical composition comprising such antibodies. The present invention includes a method of inhibiting cancer cell growth comprising administering such antibodies into a subject. The present invention also provides a method of treating cancer or psoriasis in a subject in need of such a treatment by administering such antibodies to said subject in a pharmaceutically effective amount.
L'invention porte sur des anticorps anti-AR, de préférence des anticorps monoclonaux humanisés présentant les séquences d'acides nucléiques révélées dans la description, sur des préparations pharmaceutiques contenant lesdits anticorps et sur un procédé inhibant la croissance des cellules cancéreuses consistant à administrer lesdits anticorps à un sujet. L'invention porte également sur une méthode de traitement du cancer et du psoriasis chez un patient le nécessitant consistant à lui administrer lesdits anticorps en quantité à efficacité pharmaceutique.
Hinton Paul R.
Kumar Shankar
Landolfi Nicholas F.
Tsurushita Naoya
Pdl Biopharma Inc.
Protein Design Labs Inc.
Smart & Biggar
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