Immunoconjugates and humanized antibodies specific for...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/13 (2006.01) A61K 47/48 (2006.01) C07K 16/00 (2006.01) C07K 16/30 (2006.01) C07K 16/46 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2195557

Chimeric and humanized LL2 monoclonal antibody, isolated DNAs encoding these antibodies, vectors containing the DNA and conjugates of chimeric and humanized chimeric LL2 antibodies with cytotoxic agents or labels for use in therapy and diagnosis of B-cell lymphomas and leukemias.

Anticorps LL2 monoclonal, chimère et de type humain, ADNs isolés codant lesdits anticorps, vecteurs contenant l'ADN et conjugués d'anticorps LL2 chimères et de type humain avec des agents cytotoxiques ou des marqueurs, conçus pour s'utiliser dans la thérapie et le diagnostic de lymphomes malins à cellules B et de leucémies.

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