C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/87 (2006.01) C12N 15/11 (2006.01) C12N 15/88 (2006.01)
Patent
CA 2303406
The subject invention finds utility in the area of gene therapy of diseases. More specifically, the invention concerns the making of non-viral vector which can bind to desired DNA to form a combination useful to transfect diseased mitochondria of human or animal cells. The non-viral vector comprises a dequalinium salt subjected to standard liposome production procedures to obtain the vector named DQAsomes.
La présente invention trouve une utilité dans le domaine de la thérapie génique de maladies. Plus spécifiquement, l'invention concerne la production d'un vecteur non viral pouvant se fixer à l'ADN voulu pour former une combinaison utile pour transfecter des mitochondries malades de cellules humaines ou animales. Le vecteur non viral comprend un sel de déqualinium soumis à des techniques classiques de production de liposomes afin d'obtenir le vecteur appelé DQAsomes.
Hughes Jeffrey Allen
Lasch Jurgen
Rowe Thomas Cardon
Weissig Volkmar
Macrae & Co.
University Of Florida
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