A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 33/14 (2006.01) A61K 31/505 (2006.01) A61K 31/7105 (2006.01) A61P 31/00 (2006.01)
Patent
CA 2569091
There is provided methods and uses for promoting cell death, when combined with chemotherapeutic agents, in an abnormally proliferating cell, and for treating a proliferative disorder in a subject, which methods and uses involve contacting a cell with, or administering to a subject, an agent that modulates glycogen synthase kinase-3.beta. activity to a cell that is being treated with a chemotherapeutic agent.
La présente invention concerne des méthodes et des utilisations correspondantes qui favorisent la mort cellulaire, lorsqu'on les combine à des agents chimiothérapeutiques, dans une cellule proliférant de manière anormale et qui servent à traiter une maladie proliférative chez un sujet. Ces procédés et leurs utilisations consistent à mettre en contact une cellule avec un agent modulateur ou bien à administrer à un sujet un tel agent modulateur qui module l'activité de la glycogène synthase kinase-3ß pour une cellule traitée avec un agent chimiothérapeutique.
Agency For Science Technology And Research
Smart & Biggar
LandOfFree
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