Novel triterpenic acid derivative and preparation for...

Details Novel triterpenic acid derivative and preparation for... Novel triterpenic acid derivative and preparation for...

C - Chemistry, Metallurgy

07

J

C07J 63/00 (2006.01) A61K 8/55 (2006.01) A61K 31/661 (2006.01) A61P 17/16 (2006.01) A61Q 19/02 (2006.01)

Patent

CA 2611435

In a triterpenic acid having hydroxyl groups, at least one of the hydroxyl groups is phosphatized to produce a phosphatized triterpenic acid and/or a salt thereof, thereby improving the solubility of the triterpenic acid in a preparation for external application for the skin and allowing the physiological activity of the triterpenic acid to be exerted satisfactorily. The phosphatized triterpenic acid is preferably, for example, ursolic acid phosphate and/or a salt thereof. The preparation for external application for the skin is preferably a cosmetic, particularly preferably a medicated cosmetic.

Selon la présente invention, dans un acide triterpénique ayant des groupes hydroxyle, au moins un des groupes hydroxyle est phosphaté de façon à produire un acide triterpénique phosphaté et/ou un sel de celui-ci, améliorant de ce fait la solubilité de l'acide triterpénique dans une préparation pour une application externe sur la peau et permettant à l'activité physiologique de l'acide triterpénique d'être exercée d'une manière satisfaisante. L'acide triterpénique phosphaté est de préférence, par exemple, un phosphate de l~acide ursolique et/ou un sel de celui-ci. La préparation pour une application externe sur la peau est de préférence un produit de beauté, de manière plus particulièrement préférée, un produit de beauté médicamenté.

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