Polypeptide, use thereof and method for producing thereof

Details Polypeptide, use thereof and method for producing thereof Polypeptide, use thereof and method for producing thereof

C - Chemistry, Metallurgy

12

N

C12N 15/09 (2006.01) C07K 14/47 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2412570

Polypeptides formed in a reduced amount specifically in human liver with hepatitis and a novel means of diagnosing hepatitis. Polypeptides represented by SEQ ID NO:11 or 12 which are formed in a reduced amount specifically in liver with hepatitis are found out. Based on this finding, a novel means of diagnosing hepatitis, which comprises measuring the amount of these polypeptides or mRNAs encoded thereby formed in the liver, is provided.

L'invention concerne des polypeptides produits en quantité réduite spécifiquement dans un foie humain atteint d'hépatite, ainsi qu'un nouveau moyen permettant de diagnostiquer l'hépatite. Des polypeptides représentés par le numéro de séquence 11 ou 12, produits en quantité réduite spécifiquement dans un foie atteint d'hépatite, sont découverts. Cette découverte permet la mise au point d'un nouveau moyen pour diagnostiquer l'hépatite, qui consiste à mesurer la quantité de ces polypeptides ou d'ARN messagers codés par ces polypeptides produits dans le foie.

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