Novel piperidine derivatives as modulators of chemokine...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 211/58 (2006.01) A61K 31/4468 (2006.01) A61K 31/4523 (2006.01) A61P 1/00 (2006.01) A61P 11/00 (2006.01) A61P 17/00 (2006.01) A61P 19/00 (2006.01) C07D 211/24 (2006.01) C07D 211/96 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 405/06 (2006.01) C07D 405/12 (2006.01)

Patent

CA 2508624

Compounds of formula (I) wherein R1, R2, R3, R4, A, X, m and n are as defined; compositions comprising them, processes for preparing them and their use in medical therapy (for example modulating CCR5 receptor activity in a warm blooded animal).

L'invention se rapporte à des composés de formule (I), dans laquelle R?1¿, R?2¿, R?3¿, R?4¿, A, X, m et n sont tels que définis. La présente invention concerne en outre des compositions comprenant ces composés, des procédés de préparation de ces composés, ainsi que leur utilisation dans le cadre de traitements médicaux, par exemple pour moduler l'activité du récepteur CCR5 chez un animal homéotherme.

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