Methods and kit for endometriosis screening

G - Physics – 01 – N

Patent

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G01N 33/68 (2006.01)

Patent

CA 2681933

Methods of screening a bodily sample for endometriosis are provided. The bodily sample is preferably saliva. According to one embodied method, the bodily sample is subjected to a denaturing procedure, and a property of the bodily sample observed after the denaturing procedure is evaluated for the presence or absence of a factor correlating to endometriosis as part of an endometriosis screening procedure. The methods embodied herein are preferably conducted in combinations which permit for the evaluation of at least two different physiological factors correlating to endometriosis, because women with endometriosis do not always share the same factors. Also provided are screening kits, assay methods, and systems for endometriosis screening.

L'invention concerne des procédés permettant de cribler un échantillon corporel pour endométriose. L'échantillon corporel est de préférence de la salive. Selon un procédé mis en AEuvre, l'échantillon corporel est soumis à une procédure de dénaturation, et une propriété de l'échantillon corporel observée après la procédure de dénaturation est analysé pour y détecter la présence ou l'absence d'un facteur se corrélant à l'endométriose dans le cadre d'une procédure de criblage d'endométriose. Les procédés mis en AEuvre ici sont, de préférence, conduits en combinaison, ce qui permet l'évaluation d'au moins deux facteurs physiologiques différents se corrélant à l'endométriose, car les femmes présentant une endométriose ne partagent pas toujours les mêmes facteurs. Il est également proposé des kits de criblage, des procédés d'essais, et des systèmes pour criblage d'endométriose.

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