C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 1/20 (2006.01) C12N 1/21 (2006.01) C12N 15/01 (2006.01) C12P 7/06 (2006.01) C12P 7/10 (2006.01)
Patent
CA 2721933
The present invention relates to methods of obtaining Z. mobilis mutant strains that are more tolerant to one or more inhibitors or more capable of efficiently fermenting one or more carbohydrates. Such inhibitors include ethanol, aliphatic acids, such as acetic acid, formic acid; furan derivatives, such as 2-furaldehyde, 2-furoic acid; and phenolic compounds, such as vanillin and hydroxybenzoic acid. Such carbohydrates may include xylose, arabinose, mannose and mixtures thereof. These mutant strains may be employed to, for example, effectively and efficiently prepare ethanol from biomass.
La présente invention concerne des procédés d'obtention de souches mutantes de Z. mobilis se révélant plus tolérantes à un ou plusieurs inhibiteurs ou se révélant plus aptes à favoriser une fermentation efficace d'un ou plusieurs glucides. Lesdits inhibiteurs comprennent l'éthanol; des acides aliphatiques, comme l'acide acétique, l'acide formique; des dérivés du furane, comme le 2-furaldéhyde, l'acide 2-furoïque; et des composés phénoliques, comme la vanilline et l'acide hydroxybenzoïque. Lesdits glucides peuvent comprendre le xylose, l'arabinose, le mannose et des mélanges de ceux-ci. Ces souches mutantes peuvent être utilisées pour préparer de façon efficace de l'éthanol à partir de la biomasse, par exemple.
Agrawal Manoj
Chen Rachel Ruizhen
Mao Zichao
Shin Hyun-Dong
Wang Yun
Georgia Tech Research Corporation
Smart & Biggar
LandOfFree
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