Treatment of bipolar disorders and associated symptoms

Details Treatment of bipolar disorders and associated symptoms Treatment of bipolar disorders and associated symptoms

A - Human Necessities

61

K

A61K 31/496 (2006.01) A61P 25/00 (2006.01) A61P 25/24 (2006.01)

Patent

CA 2525326

The present invention relates to a method for treatments relating to bipolar disorder in a mammal, including a human, the treatments including treatment of rapid-cycling bipolar disorder, treatment of symptoms of bipolar disorder selected from the group consisting of acute mania and depression, treatment for effecting mood stabilization; treatment for preventing relapse into bipolar episodes, and for the treatment of suicidal thoughts and tendencies associated with bipolar disorder, comprising administering to said mammal an effective amount of a compound of the formula (I): or a pharmaceutically acceptable acid addition salt thereof, wherein Ar, n, X, and Y are as defined.

L'invention porte sur un procédé pour le traitement des troubles bipolaires chez les mammifères, dont l'homme, les traitements comprenant le traitement des troubles bipolaires à cycles rapides, le traitement des symptômes des troubles bipolaires sélectionnés dans le groupe constitué par le délire et la dépression aigus, le traitement visant à stabiliser l'humeur, le traitement visant à prévenir les récidives des crises maniaco-dépressives, le traitement des pensées et des tendances suicidaires associées aux troubles bipolaires. Le procédé consiste à administrer auxdits mammifères une quantité efficace d'un composé de la formule (I) : ou son sel d'addition acide pharmaceutiquement acceptable, où Ar, n, X et Y sont tels que définis dans la formule ci-contre.

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