Glycoprotein compositions

Details Glycoprotein compositions Glycoprotein compositions

A - Human Necessities

61

K

A61K 39/395 (2006.01) C07K 16/28 (2006.01) C07K 16/32 (2006.01) C07K 16/42 (2006.01) C12P 21/08 (2006.01)

Patent

CA 2463879

The present invention concerns compositions comprising a glycoprotein having an Fc region, wherein about 80-100% of the glycoprotein in the composition comprises a mature core carbohydrate structure which lacks fucose, attached to the Fc region of the glycoprotein. The preferred glycoprotein is an antibody or immunoadhesin.

L'invention concerne des compositions comprenant une glycoprotéine ayant une région Fc. Environ 80-100 % de la glycoprotéine de la composition renferme une structure glucidique à noyau mûr manquant de fucose, fixée à la région Fc de la glycoprotéine. La glycoprotéine préférée est un anticorps ou une immunoadhésine.

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