Annelated pyrrole compounds as proton pump inhibitors for...

Details Annelated pyrrole compounds as proton pump inhibitors for... Annelated pyrrole compounds as proton pump inhibitors for...

A - Human Necessities

61

K

A61K 31/403 (2006.01) A61P 1/04 (2006.01)

Patent

CA 2484238

Inhibiting gastric proton pump in a mammal is accomplished by the use of a compound of formula (1) wherein the variables have the meaning given in the present description. A preferred compound of formula (2) is this treatment ameliorates, diminishes, actively treats, reverses or prevents any injury, damage or lesions of gastric mucosa, e.g. gastric mucosal lesions and ulceration.

Selon cette invention, l'inhibition de la pompe à protons gastrique chez un mammifère est effectuée par l'utilisation d'un composé de formule (1), dans laquelle les variables sont telles que définies dans le descriptif. Un composé préféré est le composé de formule (2). Ce traitement permet d'améliorer, diminuer, traiter activement, faire régresser ou empêcher toute blessure, tout dommage ou toute lésion de la muqueuse gastrique, par exemple des lésions et des ulcérations muqueuses gastriques.

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