Analytical method to evaluate animal models of...

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G01N 33/68 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01)

Patent

CA 2399121

The present invention relates to methods for modeling aspects of Alzheimer's disease (AD), in particular the present invention relates to methods for modeling abnormal tau hyperphosphorylation as the key step to the process of neurofibrillary degeneration and tau aggregation.

La présente invention concerne un procédé de modélisation de certains aspects de la maladie d'Alzheimer. L'invention concerne plus particulièrement un procédé de modélisation de l'hyperphosphorylation anormale de la protéine tau qui constitue un point clé du processus de dégénérescence neurofibrillaire et d'agrégation de la protéine tau.

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