Method of treating stroke with thrombolytic agent

Details Method of treating stroke with thrombolytic agent Method of treating stroke with thrombolytic agent

A - Human Necessities

61

K

A61K 38/16 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2661012

A method for treating acute ischemic stroke in a human comprises administering tenecteplase to the human in a total dose of about 0.05 to 0.5 mg/kg, given as (a) an initial bolus dose of about 0.015 to 0.15 mg/kg, followed by infusion of an amount equaling the total dose minus the initial dose over a period of about 50-90 minutes, or (b) a bolus. Also described are kits for carrying out this method.

La présente invention concerne une méthode permettant de traiter un accident ischémique cérébral aigu chez un être humain, qui consiste à administrer audit être humain une dose totale de ténectéplase s'élevant à environ 0,05 à 0,5 mg/kg, ladite dose se décomposant en (a) un bolus initial d'environ 0,015 à 0,15 mg/kg, suivi de l'injection par perfusion d'une quantité égale à la dose totale moins la dose initiale sur une période de 50 à 90 minutes environ, ou (b) un bolus. L'invention concerne également des kits permettant de mettre en oeuvre ladite méthode.

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