C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C12N 9/18 (2006.01) C12Q 1/44 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2723838
The invention relates to an in vitro or in vivo method for screening for candidate compounds for the preventive or curative treatment of acne, of seborrhoeic dermatitis or of skin disorders associated with hyperseborrhoea, comprising the determi-nation of the ability of a compound to modulate the expression or the activity of the carboxylesterase 1(CES1) and/or car-boxylesterase 3 (CES3) proteins.
L'invention concerne un procédé in vitro ou in vivo pour cribler des composés candidats destinés au traitement préventif ou curatif de l'acné, de la dermatite séborrhéique ou d'affections cutanées associées à une hyperséborrhée. Ce procédé consiste à déterminer l'aptitude d'un composé à moduler l'expression ou l'activité des protéines carboxylestérase 1 (CES1) et/ou carboxylestérase 3 (CES3).
Corvaisier Severine
Jomard Andre
Rivier Michel
Galderma Research & Development
Robic
LandOfFree
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