A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/00 (2006.01) A61K 39/395 (2006.01) A61K 39/44 (2006.01) C07K 16/24 (2006.01) C07K 16/28 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2275692
The present disclosure concerns the treatment of a patient with autoimmune disease, including AIDS, by neutralizing, removing or inhibiting different types of interferons, tumor necrosis factor, HLA class II antigens, IgE, and other pathological factors and/or their receptors, as well as neutralizing, removing or inhibiting autoantibodies, including antibodies to target cells, CD4 cells and DNA. Treatment comprises administration of an autoimmune inhibitor, or extracorporeal exposure of the patient's fluid to an immunosorbent comprising an autoimmune inhibitor, followed by return of the treated fluid to the patient; or it comprises a combined therapy involving extracorporeal immunosorption in conjunction with the administration of an autoimmune inhibitor.
L'invention concerne le traitement d'un patient souffrant d'une maladie auto-immune, dont le SIDA, qui consiste à neutraliser, supprimer ou inhiber différents types d'interférons, le facteur de nécrose tumorale, des antigènes HLA de classe II, l'IgE et d'autres facteurs pathologiques et/ou leurs récepteurs, et à neutraliser, supprimer ou inhiber des autoanticorps, dont les anticorps dirigés contre des cellules cibles, des cellules CD4 et de l'ADN. Le traitement de l'invention consiste à administrer un inhibiteur auto-immun, ou à exposer de manière extracorporelle le liquide du patient à un immuno-adsorbant comprenant un inhibiteur auto-immun, à renvoyer le liquide traité dans le patient; ou à utiliser une thérapie combinée impliquant une immunosorption extracorporelle combinée à l'administration d'un inhibiteur auto-immun.
Skurkovich Boris
Skurkovich Simon V.
Advanced Biotherapy Concepts Inc.
Gowling Lafleur Henderson Llp
LandOfFree
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