Treatment of ovarian estrogen dependent conditions

A - Human Necessities – 61 – K

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A61K 38/09 (2006.01)

Patent

CA 2182183

A method of treating an ovarian estrogen dependent condition such as endometriosis, uterine leiomyomata, PMS or DUB involving the administration of gonadotropin releasing hormone analog and the administration of antiprogestin, which will provide a therapeutic method for long term treatment without rapid loss of bone density, as occurs using GnRH analogs alone.

Un procédé pour traiter une pathologie dépendant des oestrogènes ovariens, telle que l'endométriose, les fibromyomes utérins, le syndrome prémenstruel ou les hémorragies utérines dysfonctionnelles, comprend l'administration d'un analogue de la gonadolibérine et l'administration d'une anti-progestérone, en vue de constituer un procédé thérapeutique pour un traitement à long terme sans perte rapide de densification osseuse, comme c'est le cas avec des analogues de GnRH seuls.

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