Method of inhibiting carcinogenesis by treatment with...

A - Human Necessities – 61 – K

Patent

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A61K 31/70 (2006.01) A61K 31/12 (2006.01) A61K 31/56 (2006.01) A61K 31/565 (2006.01) A61K 31/66 (2006.01)

Patent

CA 2117532

A method of combatting cancer in a subject comprising administering to said subject dehydroepiandrosterone (DHEA) or an analog thereof in an amount effective to combat cancer is disclosed in which heart failure induced by the DHEA or analog thereof is combatted by administering to the subject a ubiquinone, in an amount effective to combat heart failure induced by the DHEA or analog thereof. A preferred DHEA analog for carrying out the invention is 16 alpha-fluoroepiandrosterone, and a preferred ubiquinone for carrying out the invention is Coenzyme Q10.

L'invention se rapporte à un procédé pour combattre le cancer chez un sujet, et qui consiste à administrer audit sujet de la déshydroépiandrostérone (DHEA) ou un analogue de celle-ci en une dose efficace pour combattre le cancer. L'insuffisance cardiaque induite par la DHEA ou un analogue de celle-ci est combattue lorsqu'on administre à un sujet une coenzyme Q en une dose suffisante. Un analogue préféré de la DHEA pour la mise en oeuvre de l'invention est la 16-alpha-fluoroépiandrostérone, et une coenzyme Q préférée est la coenzyme Q10.

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