Isolation of a cell-specific internalizing peptide that...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 7/08 (2006.01) A61K 31/00 (2006.01) A61K 38/10 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 51/08 (2006.01) A61P 35/00 (2006.01) C12N 15/11 (2006.01) G01N 33/574 (2006.01) G01N 33/60 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2414650

The present invention provides a tumor-homing peptide that can target cancer and or tumor tissues. The peptide is uptaken by certain specific cancer cell types. The invention describes methods to achieve targeted delivery of anticancer drugs conjugated to this peptide for anticancer therapy. The invention also describes methods for using the peptide for the diagnosis and imaging of cancer and tumor tissues.

L'invention concerne un peptide se logeant dans une tumeur, pouvant cibler des tissus cancéreux et/ou tumoraux. Ce peptide est absorbé par certains types spécifiques de cellules cancéreuses. L'invention concerne également des procédés permettant la libération ciblée de médicaments anti-cancer conjugués au peptide susmentionné aux fins d'une thérapie anti-cancer. L'invention concerne également des procédés permettant d'utiliser le peptide pour le diagnostic et la représentation des tissus cancéreux et tumoraux.

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