Piperidine derivatives as renin inhibitors

C - Chemistry – Metallurgy – 07 – D

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C07D 413/14 (2006.01) A61K 31/538 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2570920

The application relates to novel substituted piperidines of the general formula (I) in which R1, R2, R3, R4, W, X, Z, m and n are each as defined in detail in the description, to a process for their preparation and to the use of these compounds as medicines, in particular as renin inhibitors.

Nouvelles pipéridines substituées de formule générale (I), dans laquelle R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, W, X, Z, m et n sont tels que définis en détail dans le descriptif, leur procédé de préparation et utilisation de ces composés comme médicaments, notamment comme inhibiteurs de la rénine.

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