Dry immunoassay analytical element comprising monodispersed...

G - Physics – 01 – N

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G01N 33/577 (2006.01) G01N 33/543 (2006.01) G01N 33/551 (2006.01) G01N 33/78 (2006.01) G01N 33/94 (2006.01)

Patent

CA 2013014

-0- DRY IMMUNOASSAY ANALYTICAL ELEMENT COMPRISING MONODISPERSED BEADS Abstract of the Disclosure Herein is disclosed an analytical element for immunoassays comprising a support and a spreading layer character- ized in that the element contains, a) a first population of relatively large polymeric beads having a diameter in the range of 10 to 200 µm to facilitate uniform spreading of liquids applied to the element; and b) a second population of relatively small polymeric beads having (i) a diameter in the range of 0.1 to 5 µm; (ii) receptors covalently bound to the bead surface through surface reactive groups; and (iii) surfaces which are free of residual materials.

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