Bcl-2-like polynucleotides, polypeptides, and antibodies

Details Bcl-2-like polynucleotides, polypeptides, and antibodies Bcl-2-like polynucleotides, polypeptides, and antibodies

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07H 21/04 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2398255

The present invention relates to novel human Bcl-2-like polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human Bcl-2-like polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human Bcl-2-like polypeptides.

L'invention concerne de nouveaux polypeptides humains semblables à Bcl-2 et des acides nucléiques isolés contenant les régions codantes des gènes codant ces polypeptides. Elle concerne également des vecteurs, des cellules hôtes, des anticorps et des procédés de recombinaison servant à produire ces polypeptides humains semblables à Bcl-2. Elle concerne, de plus, des procédés diagnostiques et thérapeutiques utiles pour diagnostiquer et traiter des maladies apparentées à ces nouveaux polypeptides humains semblables à Bcl-2.

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