Liquid human growth hormone formulation containing...

Details Liquid human growth hormone formulation containing... Liquid human growth hormone formulation containing...

A - Human Necessities

61

K

A61K 38/27 (2006.01) A61K 47/30 (2006.01) A61P 5/06 (2006.01)

Patent

CA 2540172

A stable pharmaceutically acceptable aqueous formulation containing human growth hormone, a buffer, polyethylene glycol, a tonicifier such as a sugar alcohol, and optionally, an antimicrobial agent and optionally, a chelating agent. Also disclosed are associated means and methods for preparing, storing and using such formulations.

L'invention concerne une formulation aqueuse stable, pharmaceutiquement acceptable, contenant de l'hormone de croissance humaine, un tampon, du polyéthylène glycol, un régulateur d'isotonicité, par exemple un alcool de sucre et, éventuellement, un agent antimicrobien et, éventuellement, un agent de chélation. L'invention concerne également des moyens et procédés associés de préparation, de stockage et d'utilisation de telles formulations.

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