A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/5377 (2006.01) A61K 31/135 (2006.01) A61K 31/138 (2006.01) A61K 31/167 (2006.01) A61K 31/352 (2006.01) A61K 31/40 (2006.01) A61K 31/4035 (2006.01) A61K 31/436 (2006.01) A61K 31/439 (2006.01) A61K 31/4439 (2006.01) A61K 31/451 (2006.01) A61K 31/4704 (2006.01) A61K 31/519 (2006.01) A61K 31/56 (2006.01) A61K 31/58 (2006.01) A61K 38/13 (2006.01) A61K 45/06 (2006.01) A61P 37/06 (2006.01)
Patent
CA 2643130
The present invention relates to neurokinin- 1 (NK-1) receptor antagonists in combination with an inhibitor of metachromatic cell activation, such as an anti- inflammatory agent, an immunosuppressor, or a kinase inhibitor, and use of such combinations in the treatment of disorders associated with activation of metachromatic cells. Disorders associated with the activation of metachromatic cells include allergic/non-allergic rhinitis, allergic/non-allergic asthma, allergic/non-allergic urticaria, immuno-infiammatory disorders, metachromatic cell-related autoimmune disorders, transplant rejection, and other metachromatic cell-related disorders.
L'invention concerne des antagonistes récepteur de la neurokinine-1 (NK-1) en combinaison avec un inhibiteur d'activation des cellules métachromatiques, tel qu'un anti-inflammatoire, un immunosuppresseur, ou un inhibiteur de kinase, et l'utilisation de ces combinaisons dans le traitement de troubles associés à l'activation des cellules métachromatiques. Les troubles associés à l'activation des cellules métachromatiques sont notamment la rhinite allergique/non allergique, l'asthme allergique/non allergique, l'urticaire allergique/non allergique, les troubles immuno-inflammatoires, les troubles auto-immuns associés aux cellules métachromatiques, le rejet de greffe, et d'autres troubles associés aux cellules métachromatiques.
Favret Sandra
Lefort Bertrand
Maghni Karim
Ouaked Nadia
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Valorisation Recherche Hscm Limited Partnership
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