Polypeptides derived from the human immunodeficiency virus...

Details Polypeptides derived from the human immunodeficiency virus... Polypeptides derived from the human immunodeficiency virus...

C - Chemistry, Metallurgy

12

N

C12N 9/16 (2006.01) C07K 14/16 (2006.01) C07K 16/10 (2006.01) C12N 11/00 (2006.01) G01N 33/569 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2105664

A polypeptide of the formula: X-Glu-Thr-Gly-Gln-Glu-Thr-Ala-Tyr-Phe-Ile-Leu-Lys-Leu-Ala-Gly-Arg-Trp-Pro-Val-Lys- Z wherein X is a chain of from 1 to 20 amino acid residues or an amino-terminal group and Z is a chain of from 1 to 20 amino acid residues or a carboxy-terminal group. The polypeptide immunologically mimics HIV endonuclease.

Polypeptide de formule X-Glu-Thr-Gly-Gln-Glu-Thr-Ala-Tyr-Phe-Ile-Leu-Lys- Leu-Ala-Gly-Arg-Trp-Pro-Val-Lys-Z, où X est une chaîne de 1 à 20 amino-acides ou un groupe amino terminal, et Z une chaîne de 1 à 20 amino-acides ou un groupe carboxy terminal. Le polypeptide mime immunologiquement l'endonucléase de VIH.

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