Cosmid dna constructs and methods of making and using the same

A - Human Necessities – 61 – K

Patent

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Details

A61K 48/00 (2006.01) A61K 39/00 (2006.01) A61K 39/245 (2006.01) C12N 15/00 (2006.01) C12N 15/11 (2006.01) C12N 15/31 (2006.01) C12N 15/38 (2006.01)

Patent

CA 2395435

Methods of inducing immune responses in individuals against a pathogen are disclosed. Methods of treating individuals susceptible to or suffering from a disease associated with a genetic defect which results in the non-production or under production of a protein or the production of a non-functioning or partially functioning protein are disclosed. Methods of delivering a protein to an individual are disclosed. Pharmaceutical compositions that comprise cosmids are disclosed.

L'invention concerne une méthode d'induction d'une réponse immune chez des individus contre un agent pathogène. L'invention concerne également des méthodes de traitement d'individus prédisposés à une maladie ou souffrant d'une maladie associée à un défaut génétique résultant de la non-production ou de la sous-production d'une protéine ou de la production d'une protéine qui ne fonctionne pas ou partiellement. L'invention concerne également des méthodes d'administration d'une protéine à un individu. L'invention concerne également des compositions pharmaceutiques comprenant des cosmides.

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