Methods of using discodermolide compounds

Details Methods of using discodermolide compounds Methods of using discodermolide compounds

A - Human Necessities

61

K

A61K 31/366 (2006.01) A61P 35/00 (2006.01) C07D 309/30 (2006.01)

Patent

CA 2233716

Novel lactone compounds from the marine sponge Discodermia dissoluta have been isolated. These compounds and their analogs have been shown to have activity against mammalian cancer cells, and can be used in treating human patients which host cancer cells, including leukemia, melanoma, and breast, colon, CNS, and lung tumors.

De nouveaux composés de lactone tirés de l'éponge marine Discodermia dissoluta ont été isolés. Il a été démontré que ces composés et leurs analogues possèdent une action contre les cellules cancéreuses chez les mammifères et peuvent servir à traiter des sujets humains ayant des cellules cancéreuses, notamment la leucémie, les mélanomes, et les tumeurs du sein, du côlon, du système nerveux central et des poumons.

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