3-quinuclidine derivatives

Details 3-quinuclidine derivatives 3-quinuclidine derivatives

C - Chemistry, Metallurgy

07

D

C07D 453/02 (2006.01) A61K 31/445 (2006.01)

Patent

CA 2059477

Abstract The invention relates to a 3-quinuclidine derivative having the formula I Image I wherein X is O or S, and R represents one to five sub- stituents independently selected from hydrogen, hydroxy, lower alkyl, lower alkoxy, lower aralkyloxy, lower alkanoyloxy, halogen, NO2, CF3, CN, NR1R2, and COR3, which R1 and R2 are independently selected from hydrogen, lower alkyl, and lower alkanoyl, and R3 is selected from OH, lower alkyl, lower alkoxy, and NR4R5, wherein R4 and R5 are independently hydrogen or lower alkyl; or pharmaceutically acceptable salts thereof.

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