Antagonists for treatment of cd11/cd18 adhesion receptor...

C - Chemistry – Metallurgy – 07 – D

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C07D 333/40 (2006.01) A61K 31/381 (2006.01) A61K 31/63 (2006.01) A61P 11/06 (2006.01) A61P 29/00 (2006.01) A61P 37/06 (2006.01) C07C 235/84 (2006.01) C07C 237/22 (2006.01) C07C 237/42 (2006.01) C07C 271/22 (2006.01) C07C 271/28 (2006.01) C07C 275/28 (2006.01) C07C 275/42 (2006.01) C07C 311/46 (2006.01) C07D 207/34 (2006.01) C07D 209/08 (2006.01) C07D 209/20 (2006.01) C07D 277/54 (2006.01) C07D 307/54 (2006.01) C07D 333/34 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2325986

Compounds of the general structure D-L-B-(AA), for example (A), that are useful for treating Mac-1 or LFA-1-mediated disorders such as inflammatory disorders, allergies, and autoimmune diseases are provided.

L'invention concerne des composés qui correspondent à la structure générale D-L-B-(AA), par exemple à la structure (A), et sont utiles pour traiter des troubles induits par LFA-1 ou Mac-1, tels que des troubles inflammatoires, des allergies et des maladies auto-immunes.

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