Oral drug delivery system

Details Oral drug delivery system Oral drug delivery system

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 9/58 (2006.01) A61K 9/64 (2006.01)

Patent

CA 2473847

There is disclosed an oral delivery system, which comprises: a sachet at least partially formed from at least one microporous or permeable membrane, and defining a cavity; a physiologically active substance dissolved or dispersed in a liquid or gel, within the cavity, the microporous or permeable membrane being in contact with the liquid or gel and being permeable to the physiologically active substance in the liquid or gel; and an encapsulating layer surrounding the sachet; characterised in that either: a) the membrane is hydrophilic and the contents of the sachet are hydrophobic; or b) the membrane is hydrophobic and the contents of the sachet are hydrophilic; whereby, in use, the encapsulating layer is first dissolved in the gastro-intestinal tract (GIT) and thereafter passage of the physiologically active substance into the GIT through the membrane is rate-controlled. A method of manufacturing the oral delivery system is also disclosed.

L'invention concerne un système d'administration orale, comprenant un sachet au moins partiellement formé d'une membrane microporeuse ou perméable et définissant une cavité ; une substance physiologiquement active dissoute ou dispersée dans un liquide ou un gel, à l'intérieur de la cavité, la membrane microporeuse ou perméable étant en contact avec le liquide ou le gel et étant perméable à la substance physiologiquement active dans le liquide ou le gel ; et une couche d'encapsulation entourant le sachet. Ledit système se caractérise en ce que a) la membrane est hydrophile et le contenu du sachet est hydrophobe ; ou b) la membrane est hydrophobe et le contenu du sachet est hydrophile. Au cours de son utilisation, la couche d'encapsulation est d'abord dissoute dans le tractus gastro-intestinal (GIT), puis le débit du passage de la substance physiologiquement active dans le GIT à travers la membrane est réglé. L'invention concerne également un procédé de fabrication de ce système d'administration orale.

Affiliated with

Also associated with

Rating

Oral drug delivery system does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Oral drug delivery system, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Oral drug delivery system will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1369226