Phosphodiesterase 4 inhibitors, including n-substituted...

C - Chemistry – Metallurgy – 07 – D

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C07D 213/74 (2006.01) A61K 31/443 (2006.01) A61K 31/444 (2006.01) A61K 31/506 (2006.01) A61P 25/00 (2006.01) C07D 277/28 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2548824

PDE4 inhibition is achieved by novel compounds, e.g., N-substituted diarylamine analogs. The compounds of the present invention are of Formula (I), wherein A, B, D, R1, R2, R3 and R4 are as defined herein.

La présente invention se rapporte à de nouveaux composés, par exemple des analogues de diarylamines N-substituées, qui ont une activité inhibitrice de la PDE4. Les composés selon l'invention sont représentés par la formule (I), dans laquelle A, B, D, R?1¿, R?2¿, R?3¿ et R?4¿ sont tels que définis dans le descriptif de l'invention.

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