C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/18 (2006.01) C07K 7/08 (2006.01) C07K 14/47 (2006.01) C12P 21/08 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2387864
Nuclear matrix proteins (NMP) which are characterized by a defined expression in tissue, particularly prostate tissue, are provided. These NMPs are useful markers in diagnosing and monitoring the stage of malignancy of a cell and treating cell proliferative disorders associated with the NMP. Also provided are substantially purified polypeptides and nucleotide sequences encoding the NMPs of the invention.
L'invention concerne des protéines de matrice nucléaire (PMN) qui sont caractérisées par une expression définie dans le tissu, en particulier dans le tissu de la prostate. Ces PMN sont des marqueurs utiles pour le diagnostic et la surveillance du degré de malignité d'une cellule, et pour le traitement des maladies à prolifération cellulaire associées aux PMN. L'invention concerne également des polypeptides sensiblement purifiés et des séquences nucléotidiques codant pour ces PMN.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
University Of Pittsburgh
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