Novel compositions of lipids and stabilizing materials

Details Novel compositions of lipids and stabilizing materials Novel compositions of lipids and stabilizing materials

A - Human Necessities

61

K

A61K 49/00 (2006.01) A61B 8/13 (2006.01) A61K 9/10 (2006.01) A61K 9/127 (2006.01) A61K 47/44 (2006.01) A61K 47/48 (2006.01) A61K 49/22 (2006.01)

Patent

CA 2217494

Compositions comprising, in an aqueous carrier, a lipid and a material which is capable of stabilizing the composition. The stabilizing material is associated non-covalently with said lipid and is present in an amount sufficient to coat the lipid but insufficient to raise the viscosity of the composition. The compositions are particularly suitable for use in diagnostic applications, including ultrasound. The compositions can take the form of vesicular compositions, such as micelles and liposomes.

Compositions constituées, dans un support aqueux, d'un lipide et d'une substance capable de stabiliser la composition. La substance de stabilisation est associée de façon non covalente avec ce lipide, et est présente en quantité suffisante pour enrober le lipide, mais insuffisante pour augmenter la viscosité de la composition. Ces compositions sont particulièrement adaptées pour les applications diagnostiques, notamment les procédés par ultrasons. Ces compositions peuvent prendre la forme de compositions vésiculaires, telles que micelles et liposomes.

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