Soluble hla cross-match

Details Soluble hla cross-match Soluble hla cross-match

G - Physics

01

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G01N 33/80 (2006.01) G01N 33/543 (2006.01) G01N 33/564 (2006.01) G01N 33/569 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2103151

2103151 9221978 PCTABS00017 Soluble HLA cross-matches are determined by providing for antibodies or ligand bound to a solid substrate specific for at least one HLA allele and detecting complexes between either donor or recipient HLA antigens and recipient or donor antibodies, respectively, or reference HLA and patient antibodies, particularly IgG antibodies. Conveniently, anti-human immunoglobulin (Ig), particularly human IgG, conjugates are employed where the anti-human Ig is conjugated with a label capable of providing a detectable signal to permit detection of human anti-HLA bound to said solid substrate.

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