Quinoline derivatives as ligands for the neuropeptide y...

Details Quinoline derivatives as ligands for the neuropeptide y... Quinoline derivatives as ligands for the neuropeptide y...

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) A61K 31/4709 (2006.01) A61K 31/55 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) A61P 19/02 (2006.01) C07D 215/42 (2006.01) C07D 401/14 (2006.01) C07D 413/04 (2006.01) C07D 491/10 (2006.01)

Patent

CA 2446324

Compounds of formula (I) as well as pharmaceutically acceptable salts and esters thereof, wherein R1, R2, R3, R4, R5 and A have the significance given in claim 1, can be used in the form of pharmaceutical preparations for the treatment or prevention of arthritis, cardiovascular diseases, diabetes, renal failure, eating disorders and obesity.

L'invention concerne des composés de formule (I), ainsi que leurs sels et esters pharmaceutiquement acceptables, dans laquelle R?1¿, R?2¿, R?3¿, R?4¿, R?5¿ et A ont les significations spécifiées dans la revendication 1. Ces composés peuvent être utilisés, sous la forme de préparations pharmaceutiques, pour le traitement ou la prévention de l'arthrite, de maladies cardiovasculaires, du diabète, d'insuffisances rénales, de dérèglements alimentaires et de l'obésité.

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