A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/127 (2006.01) A61K 47/18 (2006.01)
Patent
CA 2377422
This invention describes a method for preparing pharmaceutically usable compositions comprising periodic structures consisting of polyelectrolytes sandwiched between lipid aggregates having at least one charged component which is characterised in that a suspension of non-periodic, preferably mono- or bilayer like, lipid aggregates, a solution of polyelectrolyte molecules, and a solution of oligovalent linkers are separately made and then mixed to form said periodic structures, the simultaneous presence of said components catalysing the formation of controlling the rate of formation of said periodic structures comprising at least one layer of lipid component associated with a layer of polyelectrolyte molecules.
La présente invention concerne un procédé de préparation de compositions utilisables sur le plan pharmaceutique comportant des structures périodiques constituées de polyélectrolytes comprises entre des agrégats lipidiques possédant au moins un composant chargé caractérisé par une suspension d'agrégats lipidiques non périodiques, de préférence, de type monocouche ou bicouche, une solution de molécules polyélectrolytes, et une solution de lieurs oligovalents fabriqués séparément, puis mélangés afin de former lesdites structures périodiques, la présence simultanée des composants catalysant la formation ou réglant la vitesse de formation desdites structures périodiques comprenant au moins une couche de composant lipidique associé à une couche de molécules polyélectrolytes.
Cevc Gregor
Huebner Stefan
Borden Ladner Gervais Llp
Cevc Gregor
Huebner Stefan
Idea Ag
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