Novel heteroaryl fused cyclic amines

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 471/04 (2006.01) A61K 31/4162 (2006.01) A61K 31/4355 (2006.01) A61K 31/4375 (2006.01) A61P 7/02 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2614401

The invention is concerned with novel heteroaryl fused cyclic amines of formula (I) wherein A, X1 to X3, Y1 to Y3, Z, R1, R2, m and n are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit the coagulation factor Xa and can be used as medicaments.

L'invention concerne de nouvelles amines cycliques fusionnés avec hétéroaryle représentées par la formule (I), dans laquelle A, X1 à X3, Y1 à Y3, Z, R1, R2, m et n sont tels que définis dans le descriptif et dans les revendications, ainsi que des sels physiologiquement acceptables desdites amines. Ces composés inhibent le facteur de coagulation Xa et peuvent être utilisés comme médicaments.

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