Substituted 2-pyrrolidin-2-yl-1h-indole derivatives for...

Details Substituted 2-pyrrolidin-2-yl-1h-indole derivatives for... Substituted 2-pyrrolidin-2-yl-1h-indole derivatives for...

C - Chemistry, Metallurgy

07

D

C07D 403/04 (2006.01) A61K 31/4025 (2006.01) A61K 31/404 (2006.01) A61P 25/06 (2006.01) A61P 25/28 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 493/08 (2006.01)

Patent

CA 2469346

The invention relates to the substituted 2-pyrrolidine-2-yl-1H-indole derivatives of the formula (I), to methods for their production, to drugs containing these compounds, and to the use of 2- pyrrolidine-2-yl-1H-indole derivatives for the production of a drug for the inhibition of the NO synthase and for treating migraine, septicemic shock, multiple sclerosis, Parkinson's disease, Alzheimer's disease, Huntington's disease, inflammations, inflammatory pains, cerebral ischemia, diabetes, meningitis, arteriosclerosis and/or for wound healing.

L'invention concerne des dérivés substitués de 2-pyrrolidin-2-yl-1H-indole de formule (I), des procédés de production associés, des médicaments les contenant et l'utilisation de dérivés de 2-pyrrolidin-2-yl-1H-indole pour la préparation d'un médicament destiné à inhiber la NO-synthase et à traiter la migraine, le choc sceptique, la sclérose en plaques, les maladies de Parkinson, d'Alzheimer, de Huntington, des inflammations, des douleurs inflammatoires, l'ischémie cérébrale, le diabète, la méningite, l'artériosclérose et/ou à favoriser la cicatrisation.

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