Solid oral dosage form of valopi citabine (val-mcyd) and...

Details Solid oral dosage form of valopi citabine (val-mcyd) and... Solid oral dosage form of valopi citabine (val-mcyd) and...

A - Human Necessities

61

K

A61K 9/20 (2006.01) A61K 31/7052 (2006.01) C07H 19/067 (2006.01) A61K 9/10 (2006.01)

Patent

CA 2602000

A pharmaceutical composition and granulates, prepared by a wet granulation process. The pharmaceutical composition and granulates contain a therapeutic compound, e.g., the 3'-L-valine ester of .beta.-D-2'-C-methyl-riboguranosyl cytidine valopicitabine (val-mcyd) and its salts, esters, prodrugs or derivatives.

La présente invention concerne une composition pharmaceutique et des granulés, préparés par un processus de granulation par voie humide. Cette composition pharmaceutique et ces granulés contiennent un composé thérapeutique, par exemple l'ester de 3'-L-valine de ß-D-2'-C-méthyl-riboguranosyl cytidine et ses sels, ses esters, ses promédicaments ou ses dérivés.

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