Atropisomers of 3-heteroaryl-4(3h)-quinazolinones for the...

Details Atropisomers of 3-heteroaryl-4(3h)-quinazolinones for the... Atropisomers of 3-heteroaryl-4(3h)-quinazolinones for the...

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/505 (2006.01) C07D 401/04 (2006.01) C07D 403/14 (2006.01) C07D 413/14 (2006.01) C07D 417/06 (2006.01) C07D 417/14 (2006.01) C07D 491/10 (2006.01)

Patent

CA 2282279

The present invention relates to novel atropisomers of 3-heteroaryl-4(3H)- quinazolinones of formula (1a), and their pharmaceutically acceptable salts, and pharmaceutical compositions and methods of treating neurodegenerative and CNS-trauma related conditions.

L'invention concerne de nouveaux atropisomères des 3-hétéroaryl-4(3H)-quinazolinones, de formule (1a), et leurs sels pharmaceutiquement acceptables, ainsi que des compositions pharmaceutiques et des méthodes permettant de traiter les troubles neurodégénératifs et les troubles liés à un traumatisme du système nerveux central.

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