Immunological combinations for prophylaxis and therapy of...

Details Immunological combinations for prophylaxis and therapy of... Immunological combinations for prophylaxis and therapy of...

A - Human Necessities

61

K

A61K 39/106 (2006.01) A61K 39/02 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2414846

The invention relates to multivalent compositions for preventing or treating Helicobacter infections. Multivalent Helicobacter component compositions useful in prophylaxis comprises at least two, preferably three components, that are selected from AlpA, catalase, urease, 525 protease and 76K proteins. Multivalent compositions useful in therapy include in particular 76K + caatalase + 525 protease, urease + 76K + catalase + 525 protease, AlpA + 76K + catalase + 525 protease, AlpA + 76K and AlpA + catalase.

L'invention concerne des compositions multivalentes pour la prévention ou le traitement d'infections par Helicobacter. Les compositions contenant un constituant Helicobacter; multivalent utiles dans la prophylaxie comprennent au moins deux, de préférence trois constituants, sélectionnés à partir de AlpA, catalase, uréase, protéase 525 et protéines 76K. Les compositions multivalentes utiles en thérapie comprennent en particulier 76K + catalase + protéase 525, uréase + 76K + catalase + protéase 525, AlpA + 76K + catalase + protéase 525, AlpA + 76K et AlpA + catalase.

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