Tablets with controlled-rate release of active substances

Details Tablets with controlled-rate release of active substances Tablets with controlled-rate release of active substances

A - Human Necessities

61

K

167/164

A61K 9/24 (2006.01) A61K 9/20 (2006.01) A61K 31/275 (2006.01) A61K 31/55 (2006.01)

Patent

CA 2031393

Tablets with controlled-rate release of the active substances, consisting of a core of defined geometrical form containing the active substance, polymer substances which swell on contact with aqueous liquids and polymer substances with gelling properties, and a support applied to said core to partly cover its surface, the support consisting of polymer substances which are slowly soluble and/or slowly gellable in aqueous liquids, plasticizing substances, and possibly substances with an adjuvant function.

Comprimés à libération contrôlée de substances actives, comportant un noyau de forme géométrique définie contenant la substance active, des substances polymériques qui se gonflent au contact de liquides aqueux et des substances polymériques ayant des propriétés gélifiantes, et un support appliqué audit noyau pour en recouvrir partiellement la surface, le support étant composé de substances polymériques qui sont lentement solubles et/ou lentement gélifiables en liquides aqueux, en substances plastifiantes et, éventuellement, en substances jouant un rôle d'adjuvant.

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