Hirulog-like peptide and gene therapy

Details Hirulog-like peptide and gene therapy Hirulog-like peptide and gene therapy

C - Chemistry, Metallurgy

12

N

C12N 9/48 (2006.01) A61K 38/58 (2006.01) A61K 48/00 (2006.01) C07K 14/81 (2006.01) C12N 15/63 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2340461

There is provided a hirulog-like peptide. Also provided is the treatment of vascular restenosis including the steps of administering an effective amount of a hirulog-like peptide in a pharmaceutically acceptable carrier whereby administration prevents vascular restenosis. A pharmaceutical composition including a hirulog-like peptide and a pharmaceutically acceptable carrier is also provided. A vector expressing a hirulog-like peptide is also provided. Also provided by the present invention is a method of treating a patient with vascular restenosis by introducing to the patient an amount of a sequence encoding a hirulog-like peptide sufficient to prevent vascular restenosis.

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