Method for reducing pain using oncolytic viruses

A - Human Necessities – 61 – K

Patent

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Details

A61K 35/76 (2006.01) A61K 31/00 (2006.01) A61P 25/04 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2484398

The present invention provides a method for reducing pain associated with neoplasms in a mammal, comprising administering an effective amount of one or more oncolytic viruses. Preferably, the mammal also receives an analgesic, and the amount of analgesic required by the mammal is reduced when the oncolytic virus is administered. The oncolytic virus is preferably reovirus. The mammal may be additionally subject to chemotherapy, immunotherapy, hormonal and/or radiation therapy.

La présente invention concerne un procédé pour soulager la douleur liée aux néoplasmes chez un mammifère, qui consiste à administrer une quantité efficace d'un ou plusieurs virus oncolytiques. De préférence, le mammifère reçoit aussi un analgésique, et la quantité d'analgésique dont a besoin le mammifère est réduite lorsqu'un virus oncolytique est administré. Le virus oncolytique est de préférence un réovirus. Le mammifère peut être soumis à une thérapie supplémentaire telle que la chimiothérapie, l'immunothérapie, et/ou la thérapie hormonale ou par rayonnements.

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